ANALYTICAL CHEMIST

Company Overview

Alivio Therapeutics is an early-stage, biotechnology company developing novel drug formulations for treating inflammatory diseases.  Alivio’s technology platform is a proprietary delivery technology that is designed to entrap a broad array of bioactives, target them to inflamed tissue, and then release them to a greater or lesser degree based on the amount of inflammation that is present.  The technology was developed by biomaterials pioneers Jeffrey Karp, PhD and Robert Langer, ScD. The novel properties of the technology have been published twice in Science Translational Medicine.  For more information, please visit http://www.aliviotherapeutics.com. http://www.aliviotherapeutics.com.

We currently have an opening for a full-time, analytical chemist with prior laboratory experience and an interest in the development of drug delivery systems.

Key Responsibilities

  • Perform routine test methods to support research and product development, including:
    • HPLC-based analytical methods to quantify drug loading and release rates from hydrogel formulations
    • Bioananalytical assays including ELISAs and hydrogel-tissue binding
    • Formulation characterization methods including particle sizing, viscosity and product use tests
  • Coordinate analytical and toxicology testing at external contract research organizations
  • Create and manage an analytical database to tabulate testing results
  • Draft standard operating procedures and test methods
  • Create presentations and present progress to senior management
  • Maintain laboratory equipment, stock basic laboratory supplies and chemicals, and coordinate waste removal as needed
  • Maintain a clear, detailed laboratory notebook to document all experiments and findings
  • Comply with best safety practices

Required Qualifications

  • Bachelor’s Degree in Chemistry, Analytical Chemistry, Biochemistry, or related discipline
  • 2+ years of laboratory experience that includes analytical testing and characterization following SOPs
  • Experience running HPLC-based analytical methods
  • Immediate availability
  • Proficient in basic computer skills (Word, Excel, PowerPoint)
  • Strong communication, organization and technical writing skills
  • Ability to work in a small company environment

Preferred Qualifications

  • Experience performing analytical test methods for pharmaceutics or drug delivery systems
  • Experience running bioanalytical assays
  • Familiarity with ISO 13485/GMP design controls